Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | THRB | P10828 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434478 | 0.88 | ALDH1A1 (0.57) | ALDH1A1LMNATHRBSMN1; SMN2KDM4E | |
| SCHEMBL9434179 | 0.87 | GSK3B (0.68) | ALDH1A1LMNATHRBSMN1; SMN2KDM4E | |
| SCHEMBL8020581 | 0.86 | ALDH1A1 (0.74) | ALDH1A1LMNATHRBSMN1; SMN2KDM4E | |
| SCHEMBL8020587 | 0.86 | ALDH1A1 (0.74) | ALDH1A1LMNATHRBSMN1; SMN2KDM4E | |
| SCHEMBL9434748 | 0.85 | CYP1A1 (0.62) | ALDH1A1LMNATHRBSMN1; SMN2KDM4E | |
| SCHEMBL9434737 | 0.81 | ALDH1A1 (0.52) | ALDH1A1LMNATHRBSMN1; SMN2GSK3B | |
| SCHEMBL9367465 | 0.80 | ALDH1A1 (0.82) | ALDH1A1LMNATHRBSMN1; SMN2KDM4E | |
| SCHEMBL9367470 | 0.80 | ALDH1A1 (0.82) | ALDH1A1LMNATHRBSMN1; SMN2KDM4E | |
| SCHEMBL2136926 | 0.79 | ALDH1A1 (1.00) | ALDH1A1LMNATHRBSMN1; SMN2KDM4E | |
| SCHEMBL8007819 | 0.79 | ALDH1A1 (0.84) | ALDH1A1LMNATHRBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |