Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434748 | 0.83 | CYP1A1 (0.62) | ALDH1A1LMNATHRBSMN1; SMN2CYP1A2 | |
| SCHEMBL9434440 | 0.81 | LMNA (0.47) | ALDH1A1LMNATHRBSMN1; SMN2CYP1A2 | |
| SCHEMBL9433864 | 0.81 | NAPRT (0.47) | ALDH1A1LMNATHRBSMN1; SMN2CYP1A2 | |
| SCHEMBL9434693 | 0.81 | CYP1A2 (0.56) | ALDH1A1LMNATHRBSMN1; SMN2CYP1A2 | |
| SCHEMBL9434664 | 0.81 | ALDH1A1 (0.72) | ALDH1A1LMNATHRBSMN1; SMN2CYP1A2 | |
| SCHEMBL9434590 | 0.79 | P4HB (0.58) | LMNATHRBVNN1NAMPTHTT | |
| SCHEMBL9434552 | 0.79 | P4HB (0.48) | ALDH1A1LMNAVNN1NAPRTTBXAS1 | |
| SCHEMBL9434478 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LMNATHRBSMN1; SMN2CYP1A2 | |
| SCHEMBL9433920 | 0.78 | TBXAS1 (0.56) | THRBCYP1A2CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL7382581 | 0.78 | TGM2 (0.66) | ALDH1A1LMNASMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |