Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434218 | 0.88 | GSTP1 (0.46) | FFAR1ALDH1A1SMN1; SMN2PTGER4PTGER3 | |
| SCHEMBL9434756 | 0.81 | CYP3A4 (0.39) | CYP3A4CYP2C9 | |
| SCHEMBL9434194 | 0.81 | IDO1 (0.45) | LMNAPTGER1CYP3A4CYP2C9PTGER4 | |
| SCHEMBL9434742 | 0.79 | GPBAR1 (0.41) | PTGER1CYP3A4CYP2C9 | |
| SCHEMBL9433871 | 0.78 | PDE4A (0.37) | FFAR1 | |
| SCHEMBL9434701 | 0.78 | EGFR (0.40) | ALDH1A1LMNASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9434449 | 0.78 | RPS6KA3 (0.46) | FFAR1KDM4E | |
| SCHEMBL9434562 | 0.75 | SLC22A12 (0.47) | ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9433930 | 0.74 | GPBAR1 (0.36) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9433405 | 0.74 | PDE4A (0.43) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |