Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433910 | 0.90 | KDM4E (0.44) | CNR2KDM4EHSD17B10MAP2K1KMT2A | |
| SCHEMBL9434412 | 0.90 | ALDH1A1 (0.40) | CNR2KDM4EHSD17B10MAP2K1KMT2A | |
| SCHEMBL9434708 | 0.86 | CNR2 (0.38) | CNR2KDM4EHSD17B10MAP2K1KMT2A | |
| SCHEMBL9433618 | 0.86 | CACNA1B (0.38) | CNR2KDM4EHSD17B10MAP2K1KMT2A | |
| SCHEMBL9434354 | 0.85 | CNR2 (0.38) | CNR2KDM4EHSD17B10MAP2K1MAPT | |
| SCHEMBL9434181 | 0.82 | NPSR1 (0.40) | CNR2KDM4EHSD17B10MAP2K1MAPT | |
| SCHEMBL9433565 | 0.81 | KDM4E (0.38) | CNR2KDM4EHSD17B10MAP2K1KMT2A | |
| SCHEMBL9434469 | 0.81 | KDM4E (0.42) | CNR2KDM4EHSD17B10MAP2K1KMT2A | |
| SCHEMBL9433808 | 0.79 | SMN1; SMN2 (0.37) | CNR2KDM4EHSD17B10MAP2K1MAPT | |
| SCHEMBL9434131 | 0.79 | CNR2 (0.34) | CNR2KDM4EHSD17B10MAP2K1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |