Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434676 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MTNR1AMTNR1BL3MBTL1POLB | |
| SCHEMBL9009163 | 0.87 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL16040557 | 0.83 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1POLBGAAMAPT | |
| Hydrochloric Acid SCHEMBL15512772 | 0.82 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1POLBGAAMAPT | |
| SCHEMBL10344360 | 0.81 | CRHBP (0.43) | ALDH1A1MTNR1AMTNR1BL3MBTL1POLB | |
| SCHEMBL10344362 | 0.81 | CRHBP (0.43) | ALDH1A1MTNR1AMTNR1BL3MBTL1POLB | |
| SCHEMBL16435300 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MTNR1AMTNR1BL3MBTL1POLB | |
| SCHEMBL3854469 | 0.81 | SMN1; SMN2 (0.59) | ALDH1A1L3MBTL1POLBGAAMAPT | |
| SCHEMBL3854475 | 0.81 | SMN1; SMN2 (0.59) | ALDH1A1L3MBTL1POLBGAAMAPT | |
| SCHEMBL3036233 | 0.80 | RAD52 (0.51) | ALDH1A1MTNR1AMTNR1BL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |