Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344360 | 1.00 | CRHBP (0.43) | CRHBPCRHR2MTNR1AMTNR1BTSHR | |
| SCHEMBL3854469 | 0.84 | SMN1; SMN2 (0.59) | TSHRALDH1A1MAPTTDP1POLB | |
| SCHEMBL3854475 | 0.84 | SMN1; SMN2 (0.59) | TSHRALDH1A1MAPTTDP1POLB | |
| SCHEMBL9652432 | 0.82 | TSHR (0.51) | CRHBPCRHR2MTNR1AMTNR1BTSHR | |
| SCHEMBL9434676 | 0.81 | ALDH1A1 (0.41) | MTNR1AMTNR1BALDH1A1MAPTTDP1 | |
| SCHEMBL9434686 | 0.81 | ALDH1A1 (0.41) | MTNR1AMTNR1BALDH1A1MAPTTDP1 | |
| SCHEMBL10923640 | 0.78 | HCAR2 (0.59) | TSHRALDH1A1MAPTTDP1PKM | |
| SCHEMBL10344627 | 0.77 | MTNR1A (0.47) | CRHBPCRHR2MTNR1AMTNR1BTSHR | |
| SCHEMBL9312727 | 0.77 | CRHBP (0.46) | CRHBPCRHR2MTNR1AMTNR1BTSHR | |
| SCHEMBL11676179 | 0.75 | SMN1; SMN2 (0.65) | TSHRALDH1A1MAPTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230944-B1 | DIHYDROPYRIDINE-5-PHOSPHONIC ACID CYCLIC PROPYLENE ESTER | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-02-07 | — | — | EP | disclosed |
| EP-0230944-A1 | Dihydropyridine-5-phosphonic acid cyclic propylene ester | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
| WO-1987004439-A1 | DIHYDROPYRIDINE-5-PHOSPHONIC ACID CYCLIC PROPYLENE ESTER | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-07-30 | — | — | WO | disclosed |