Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434836 | 1.00 | MAPT (0.51) | MAPTNPSR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9434816 | 0.80 | MAPT (0.52) | MAPTNPSR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9433575 | 0.80 | MAPT (0.52) | MAPTNPSR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5257443 | 0.79 | L3MBTL1 (0.44) | MAPTNPSR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5257447 | 0.79 | L3MBTL1 (0.44) | MAPTNPSR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11224609 | 0.77 | MAOB (0.59) | MAPTNPSR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11224613 | 0.77 | MAOB (0.59) | MAPTNPSR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11224607 | 0.77 | MAOB (0.59) | MAPTNPSR1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9434339 | 0.76 | GLO1 (0.63) | MAPTNPSR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9434342 | 0.76 | GLO1 (0.63) | MAPTNPSR1ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |