Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433575 | 1.00 | MAPT (0.52) | MAPTSMN1; SMN2GAANPSR1RAB9A | |
| SCHEMBL11319186 | 0.85 | MAPT (0.52) | MAPTSMN1; SMN2GAANPSR1RAB9A | |
| SCHEMBL9433788 | 0.81 | ALDH1A1 (0.49) | MAPTSMN1; SMN2GAANPSR1RAB9A | |
| SCHEMBL9434836 | 0.80 | MAPT (0.51) | MAPTSMN1; SMN2GAANPSR1RAB9A | |
| SCHEMBL9434831 | 0.80 | MAPT (0.51) | MAPTSMN1; SMN2GAANPSR1RAB9A | |
| SCHEMBL9434713 | 0.79 | ALDH1A1 (0.50) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL9434495 | 0.79 | ALDH1A1 (0.50) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL9433640 | 0.79 | RAB9A (0.62) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL9433771 | 0.79 | RAB9A (0.62) | MAPTSMN1; SMN2GAARAB9ANPC1 | |
| SCHEMBL9433401 | 0.79 | MAPT (0.64) | MAPTSMN1; SMN2GAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |