Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.38 |
| ▸ | HTR3B | O95264 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435157 | 0.94 | PGR (0.43) | PGRMAPK1MAPK8KMT2AMAPK9 | |
| SCHEMBL14023791 | 0.80 | KDM4E (0.44) | PGRMAPK1MAPK8KMT2AKDM4E | |
| SCHEMBL29062452 | 0.76 | PGR (0.50) | PGRMAPK1MAPK8KMT2AMAPK9 | |
| SCHEMBL11374541 | 0.76 | RXFP1 (0.45) | MAPK1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL9434645 | 0.72 | PGR (0.54) | PGRMAPK1MAPK8KMT2AKDM4E | |
| SCHEMBL11379378 | 0.71 | ALOX15 (0.45) | MAPK1KMT2AKDM4EATMALDH1A1 | |
| SCHEMBL11384047 | 0.69 | RXFP1 (0.42) | MAPK1KMT2AHTR3AKDM4EALDH1A1 | |
| SCHEMBL6884230 | 0.68 | PGR (0.54) | PGRMAPK1MAPK8KMT2AKDM4E | |
| SCHEMBL9435161 | 0.68 | PGR (0.54) | PGRMAPK1MAPK8KMT2AMAPK9 | |
| SCHEMBL14023608 | 0.67 | MAPK8 (0.39) | MAPK1MAPK8KDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994024109-A1 | INDAZOLE DERIVATIVES AND ANTIVIRAL DRUGS THAT CONTAIN THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1994-10-27 | — | — | WO | disclosed |