Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | DRD5 | P21918 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435181 | 0.94 | PGR (0.41) | PGRKDM4EALDH1A1MAPK1TSHR | |
| SCHEMBL14023791 | 0.86 | KDM4E (0.44) | PGRKDM4EALDH1A1NPSR1CRHBP | |
| SCHEMBL11379378 | 0.76 | ALOX15 (0.45) | KDM4EALDH1A1NPSR1CRHBPCRHR2 | |
| SCHEMBL29062452 | 0.74 | PGR (0.50) | PGRKDM4EALDH1A1NPSR1MAPK1 | |
| SCHEMBL14023608 | 0.74 | MAPK8 (0.39) | KDM4EALDH1A1NPSR1CRHBPCRHR2 | |
| SCHEMBL14023674 | 0.74 | ALDH1A1 (0.37) | KDM4EALDH1A1NPSR1CRHBPCRHR2 | |
| SCHEMBL14023660 | 0.74 | NPSR1 (0.36) | KDM4EALDH1A1NPSR1CRHBPCRHR2 | |
| SCHEMBL23401070 | 0.73 | BCHE (0.53) | KDM4EALDH1A1NPSR1GAAALOX15 | |
| SCHEMBL4789265 | 0.72 | HSD17B10 (0.43) | KDM4EALDH1A1NPSR1SMN1; SMN2GAA | |
| SCHEMBL23402467 | 0.72 | BCHE (0.51) | KDM4EALDH1A1NPSR1GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994024109-A1 | INDAZOLE DERIVATIVES AND ANTIVIRAL DRUGS THAT CONTAIN THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1994-10-27 | — | — | WO | disclosed |