Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.51 |
| ▸ | DRD3 | P35462 | 12/20 | 0.51 |
| ▸ | DRD4 | P21917 | 7/20 | 0.51 |
| ▸ | DRD1 | P21728 | 7/20 | 0.51 |
| ▸ | DRD5 | P21918 | 6/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577378 | 0.87 | DRD1 (0.62) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL30299229 | 0.87 | DRD1 (0.62) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL30888625 | 0.85 | DRD1 (0.60) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL20231604 | 0.85 | DRD1 (0.60) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL4133301 | 0.85 | DRD1 (0.60) | DRD2DRD3DRD4DRD1DRD5 | |
| Methylene Chloride SCHEMBL29094368 | 0.84 | DRD1 (0.55) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL9434695 | 0.83 | DRD2 (0.56) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL31028084 | 0.83 | DRD1 (0.62) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL1506557 | 0.83 | DRD1 (0.62) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL2607471 | 0.79 | DRD1 (0.62) | DRD2DRD3DRD4DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022495-A1 | DOPAMINE D-3 AND SEROTONIN (5-HT1A) RECEPTOR LIGANDS AND IMAGING AGENTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1994-10-13 | — | — | WO | disclosed |