Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 9/20 | 0.60 |
| ▸ | DRD2 | P14416 | 8/20 | 0.60 |
| ▸ | DRD3 | P35462 | 8/20 | 0.60 |
| ▸ | DRD5 | P21918 | 8/20 | 0.60 |
| ▸ | DRD4 | P21917 | 5/20 | 0.60 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231604 | 1.00 | DRD1 (0.60) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL30888625 | 1.00 | DRD1 (0.60) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL577378 | 0.98 | DRD1 (0.62) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL30299229 | 0.98 | DRD1 (0.62) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL1506557 | 0.93 | DRD1 (0.62) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL31028084 | 0.93 | DRD1 (0.62) | DRD1DRD2DRD3DRD5DRD4 | |
| Methylene Chloride SCHEMBL29094368 | 0.90 | DRD1 (0.55) | DRD1DRD2DRD3DRD5DRD4 | |
| SCHEMBL2607471 | 0.89 | DRD1 (0.62) | DRD1DRD2DRD3DRD5DRD4 | |
| Propylamine SCHEMBL9435187 | 0.85 | DRD2 (0.51) | DRD1DRD2DRD3DRD5DRD4 | |
| Acrylonitrile SCHEMBL14856533 | 0.82 | DRD1 (0.49) | DRD1DRD2DRD3DRD5DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066357-B2 | Benzoannulene derivatives as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
| US-11066357-B2 | Benzoannulene derivatives as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
| US-20210078937-A1 | BENZOANNULENE DERIVATIVES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE | 2021-03-18 | — | — | US | disclosed |
| US-20210078937-A1 | BENZOANNULENE DERIVATIVES AS ANTIVIRAL AGENTS | SOUTHERN RESEARCH INSTITUTE | 2021-03-18 | — | — | US | disclosed |
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
| US-8394859-B2 | Combretastatin analogs with tubulin binding activity | BAYLOR UNIVERSITY (US) | 2013-03-12 | — | — | US | disclosed |
| US-20100022515-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-01-28 | — | — | US | disclosed |
| US-20090075943-A1 | Combretastatin Analogs with Tubulin Binding Activity | BAYLOR UNIVERSITY | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078937-A1 | BENZOANNULENE DERIVATIVES AS ANTIVIRAL AGENTS | ZC3HAV1, MAVS, ZC3HAV1L | DRD1 2303/4885DRD2 3915/4885DRD3 3045/4885 |
| US-20100022515-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GCGR, GPR65 | DRD1 3575/4885DRD2 2154/4885DRD3 3129/4885 |
| US-11066357-B2 | Benzoannulene derivatives as antiviral agents | ZC3HAV1, MAVS, ZC3HAV1L | DRD1 2303/4885DRD2 3915/4885DRD3 3045/4885 |
| US-10450263-B2 | Benzo annulenes as antiviral agents | MAVS, ZC3HAV1, GABBR1 | DRD1 2141/4885DRD2 3639/4885DRD3 2996/4885 |
| US-20090075943-A1 | Combretastatin Analogs with Tubulin Binding Activity | TUBB, TUBB3, TUBB1 | DRD1 4052/4885DRD2 3552/4885DRD3 3459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.