SCHEMBL577378

SCHEMBL577378

COc1ccc2c(c1)CCCC2

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 9/20 0.62
DRD2 P14416 8/20 0.62
DRD3 P35462 8/20 0.62
DRD5 P21918 8/20 0.62
DRD4 P21917 5/20 0.62
STS P08842 1/20 0.55
CHRNA7 P36544 1/20 0.55
ALDH1A1 P00352 1/20 0.53
BCL2 P10415 1/20 0.52
NPC1 O15118 1/20 0.51
POLB P06746 1/20 0.51
RAB9A P51151 1/20 0.51
KDM1A O60341 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30299229 1.00 DRD1 (0.62) DRD1DRD2DRD3DRD5DRD4
SCHEMBL30888625 0.98 DRD1 (0.60) DRD1DRD2DRD3DRD5DRD4
SCHEMBL4133301 0.98 DRD1 (0.60) DRD1DRD2DRD3DRD5DRD4
SCHEMBL20231604 0.98 DRD1 (0.60) DRD1DRD2DRD3DRD5DRD4
SCHEMBL31028084 0.95 DRD1 (0.62) DRD1DRD2DRD3DRD5DRD4
SCHEMBL1506557 0.95 DRD1 (0.62) DRD1DRD2DRD3DRD5DRD4
Methylene Chloride SCHEMBL29094368 0.92 DRD1 (0.55) DRD1DRD2DRD3DRD5DRD4
SCHEMBL2607471 0.91 DRD1 (0.62) DRD1DRD2DRD3DRD5DRD4
Propylamine SCHEMBL9435187 0.87 DRD2 (0.51) DRD1DRD2DRD3DRD5DRD4
Acrylonitrile SCHEMBL14856533 0.84 DRD1 (0.49) DRD1DRD2DRD3DRD5DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730810-A Synthesis method of medical intermediate 6-methoxy-1-tetralone 上海常丰生物医药科技有限公司 2023-09-12 CN claimed
CN-114249352-A Method for treating wastewater generated in production of 6-methoxy tetralone 沈阳化工研究院有限公司 2022-03-29 CN claimed
US-20080182333-A1 Fluorescent chemosensors for metals based on dipyrrins STC.UNM 2008-07-31 US claimed
EP-0204975-B1 PROCESS FOR PREPARING SUBSTITUTED TETRALONES ETHYL CORPORATION (US) 1991-07-17 EP claimed
EP-0204975-A2 Process for preparing substituted tetralones ETHYL CORPORATION (US) 1986-12-17 EP claimed
US-4603221-A 6-ALKOXYTETRALIN, TRANSITION METAL SALT, TERTIARY AMINE, AMMONIUM OR ALKALI METAL PERSULFATE, OXIDATION ETHYL CORPORATION (US) 1986-07-29 US claimed
JP-61003892-A None JP disclosed
CN-121824281-A Method for preparing 6-methoxy-1-tetralone by photocatalytic oxidation 江苏信和生物医药有限公司 2026-04-10 CN disclosed
EP-4706820-A1 ENANTIOSELECTIVE C-H AMINATION WITH IRON PHTHALOCYANINE AND DIAMMONIUM TEMPLATE CATALYSTS The University Of Hong Kong (CN) 2026-03-11 EP disclosed
US-20260062406-A1 Benzisoxazole Sulfonamide Derivatives PFIZER (US) 2026-03-05 US disclosed
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
EP-4692094-A1 SULFONAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF Beijing Konruns Pharmaceutical Co., Ltd. (CN) 2026-02-11 EP disclosed
EP-4680226-A2 ACYLSULFONAMIDE KAT6A INHIBITORS Olema Pharmaceuticals, Inc. (US) 2026-01-21 EP disclosed
EP-0088346-B1 2-AMINOMETHYL-PHENOL DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1985-06-05 EP disclosed
WO-1984004247-A1 BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES RORER INT OVERSEAS (US) 1984-11-08 WO disclosed
EP-0088345-A2 2-Aminomethyl-6-sulfamoylphenol derivatives, process for their preparation, their use and pharmaceutical preparations based on these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1983-09-14 EP disclosed
EP-0088346-A2 2-Aminomethyl-phenol derivatives, process for their preparation, their use and pharmaceutical compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1983-09-14 EP disclosed
US-4294992-A Process for the production of alkyl aryl ethers THE SOUTHLAND CORPORATION (US) 1981-10-13 US disclosed
US-4048330-A Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia SYNTEX CORPORATION (US) 1977-09-13 US disclosed
US-4009197-A 2-(6-Substituted-2'-naphthyl) acetic acid derivatives and the salts and esters thereof SYNTEX CORPORATION (PM) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B DRD1 74/4885DRD2 44/4885DRD3 100/4885
US-20260062406-A1 Benzisoxazole Sulfonamide Derivatives KAT8, KAT5, KAT7 DRD1 4521/4885DRD2 4760/4885DRD3 4607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.