Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610343 | 0.80 | ALDH1A1 (0.47) | NPC1RAB9AHPGDSMN1; SMN2POLB | |
| SCHEMBL7852208 | 0.80 | HDAC1 (0.43) | NPC1RAB9APOLBHDAC1HDAC2 | |
| SCHEMBL3818243 | 0.77 | RAB9A (0.41) | NPC1RAB9ASMN1; SMN2POLBSCD | |
| SCHEMBL7843904 | 0.77 | SCD (0.43) | NPC1RAB9ASMN1; SMN2POLBSCD | |
| SCHEMBL14643905 | 0.75 | TLR9 (0.52) | NPC1RAB9ASMN1; SMN2DAPK1HDAC1 | |
| SCHEMBL13074308 | 0.71 | CDK1 (0.42) | NPC1RAB9ASMN1; SMN2POLBSCD | |
| SCHEMBL3823809 | 0.71 | RAB9A (0.43) | NPC1RAB9AHPGDSMN1; SMN2SCD | |
| SCHEMBL25500749 | 0.71 | CDK5 (0.40) | DAPK1HDAC1HDAC2MGMT | |
| SCHEMBL8340777 | 0.71 | DAPK1 (0.46) | NPC1RAB9AHPGDDAPK1ALDH1A1 | |
| SCHEMBL13074309 | 0.71 | SCD (0.39) | NPC1RAB9ASMN1; SMN2POLBSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618923-A1 | PEPTIDE NUCLEIC ACIDS AND THEIR EFFECT ON GENETIC MATERIAL | GLAXO WELLCOME INC. (US) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993012129-A1 | PEPTIDE NUCLEIC ACIDS AND THEIR EFFECT ON GENETIC MATERIAL | GLAXO INC. (US) | 1993-06-24 | — | — | WO | disclosed |