Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RRM1 | P23921 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435493 | 1.00 | L3MBTL1 (0.56) | L3MBTL1KDM4EDRD4DRD2DRD3 | |
| SCHEMBL9098357 | 0.93 | TSHR (0.52) | L3MBTL1TSHRCYP2D6MEN1KMT2A | |
| SCHEMBL9098366 | 0.93 | TSHR (0.52) | L3MBTL1TSHRCYP2D6MEN1KMT2A | |
| SCHEMBL9098349 | 0.93 | TSHR (0.52) | L3MBTL1TSHRCYP2D6MEN1KMT2A | |
| SCHEMBL9435297 | 0.91 | MAPT (0.52) | L3MBTL1KDM4EDRD4DRD2DRD3 | |
| SCHEMBL9435300 | 0.91 | MAPT (0.52) | L3MBTL1KDM4EDRD4DRD2DRD3 | |
| SCHEMBL9435672 | 0.90 | MAPT (0.59) | — | |
| SCHEMBL9435669 | 0.90 | MAPT (0.59) | — | |
| SCHEMBL9435307 | 0.90 | DRD4 (0.58) | L3MBTL1DRD4DRD2DRD3TSHR | |
| SCHEMBL9435302 | 0.90 | DRD4 (0.58) | L3MBTL1DRD4DRD2DRD3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371088-A | 1-aryl-4-piperazinylcyclohexanecarbonitriles, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |