Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818558 | 0.77 | LMNA (0.50) | MAOANOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL2586864 | 0.74 | MAOA (0.64) | MAOANOX1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL29377505 | 0.72 | MAOA (1.00) | MAOANOX1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL231247 | 0.72 | MAOA (1.00) | MAOANOX1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL7122154 | 0.70 | MAOA (0.58) | MAOANOX1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL6651734 | 0.70 | MAOA (0.58) | MAOANOX1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL8965779 | 0.70 | MAOA (0.41) | MAOANOX1ADRA2ASLC6A2SLC6A4 | |
| SCHEMBL16892119 | 0.68 | MAOA (0.60) | MAOANOX1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL7071638 | 0.68 | MAOA (0.55) | MAOANOX1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL21402739 | 0.68 | KDM1A (0.48) | MAOAADRA2AADRA2BADRA2CCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362559-A | Improved strength and uniformity | KABUSHIKI KAISHA TOSHIBA (JP) | 1994-11-08 | — | — | US | claimed |