Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435728 | 0.77 | MAOA (0.53) | LMNAMEN1KMT2AMAOANOX1 | |
| Metiazinic Acid SCHEMBL30190433 | 0.74 | LMNA (0.59) | LMNAMEN1KMT2AMAOANOX1 | |
| Metiazinic Acid SCHEMBL150554 | 0.74 | LMNA (0.59) | LMNAMEN1KMT2AMAOANOX1 | |
| Metiazinic Acid SCHEMBL10820947 | 0.74 | LMNA (0.59) | LMNAMEN1KMT2AMAOANOX1 | |
| Metiazinic Acid SCHEMBL30697757 | 0.74 | LMNA (0.59) | LMNAMEN1KMT2AMAOANOX1 | |
| Hydrochloric Acid SCHEMBL27595175 | 0.72 | NOX1 (0.57) | NOX1BCHEMAPTACHEPOLB | |
| SCHEMBL10424259 | 0.72 | AKR1B1 (0.52) | LMNAMEN1KMT2ABCHETDP1 | |
| SCHEMBL2586864 | 0.72 | MAOA (0.64) | LMNAMEN1KMT2AMAOANOX1 | |
| SCHEMBL4080875 | 0.70 | MEN1 (0.52) | LMNAMEN1KMT2ANOX1BCHE | |
| SCHEMBL27460473 | 0.70 | MAOA (0.62) | LMNAMEN1KMT2AMAOANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250083-B1 | DOSAGE FORM WITH MEANS FOR GOVERNING RATE OF GAS FORMATION | ALZA CORPORATION (US) | 1991-12-04 | — | — | EP | disclosed |
| US-4847093-A | Dosage form with means for governing rate of gas formation | ALZA CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0250083-A2 | Dosage form with means for governing rate of gas formation | ALZA CORPORATION (US) | 1987-12-23 | — | — | EP | disclosed |
| US-4518608-A | INDOMETHALIN WITH HYDROPHILIC COMPOUND FOR PARENTERAL ADMINISTRATION | MEDIMPEX GYOGYSZERKUELKERESKEDELMI VAALLALAT (HU) | 1985-05-21 | — | — | US | disclosed |
| EP-0040899-B1 | METHOD OF DELIVERING DRUG WITH AID OF EFFERVESCENT ACTIVITY GENERATED IN ENVIRONMENT OF USE | ALZA CORPORATION (US) | 1984-09-12 | — | — | EP | disclosed |
| US-4391814-A | Derivatives of antiphlogistically effective carboxylic acids, their preparation and medicinal use | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-07-05 | — | — | US | disclosed |
| US-4344929-A | Method of delivering drug with aid of effervescent activity generated in environment of use | ALZA CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| EP-0040899-A2 | Method of delivering drug with aid of effervescent activity generated in environment of use | ALZA CORPORATION (US) | 1981-12-02 | — | — | EP | disclosed |
| US-4265874-A | Method of delivering drug with aid of effervescent activity generated in environment of use | ALZA CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |