SCHEMBL9436161

SCHEMBL9436161

O=S(=O)(O)C1(S(=O)(=O)O)C=CC(Oc2ccccc2)=CC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.34
HTT P42858 1/20 0.34
SOS1 Q07889 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
MMP1 P03956 5/20 0.33
MMP8 P22894 4/20 0.33
MMP3 P08254 3/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP7 P09237 1/20 0.33
MMP14 P50281 1/20 0.33
ADAM17 P78536 1/20 0.33
LTA4H P09960 2/20 0.32
TSHR P16473 1/20 0.32
MMP13 P45452 3/20 0.31
PGR P06401 2/20 0.31
LMNA P02545 2/20 0.31
KMT2A Q03164 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11661291 0.85 SMN1; SMN2 (0.34) SMN1; SMN2HTTSOS1CA1CA2
SCHEMBL4470306 0.81 CA1 (0.34) SMN1; SMN2HTTSOS1CA1CA2
SCHEMBL332453 0.75 PARP10 (0.35) SMN1; SMN2LTA4HTSHRPGRKMT2A
SCHEMBL447640 0.73 TSHR (0.31) SMN1; SMN2MMP2MMP7MMP14TSHR
SCHEMBL11862959 0.72 LMNA (0.35) LTA4HTSHRLMNAKMT2A
Hydrochloric Acid SCHEMBL27544049 0.72 TSHR (0.31) SMN1; SMN2MMP2MMP7MMP14TSHR
SCHEMBL9435955 0.71 HTR6 (0.39) SMN1; SMN2HTTCA1CA2MMP1
SCHEMBL16394659 0.70 HTT (0.33) SMN1; SMN2HTTPGRLMNA
SCHEMBL11192676 0.69 LTA4H (0.34) LTA4HTSHR
SCHEMBL4238594 0.69 LTA4H (0.31) LTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0581898-A1 POLYANILINE COMPOSITIONS HAVING A SURFACE/CORE DOPANT ARRANGEMENT AlliedSignal Inc. (US) 1994-02-09 EP disclosed
WO-1992018988-A1 POLYANILINE COMPOSITIONS HAVING A SURFACE/CORE DOPANT ARRANGEMENT ALLIED-SIGNAL INC. (US) 1992-10-29 WO disclosed
US-4490487-A SO3 /Imide adducts, process for their preparation and their use as sulphonating agents BAYER AKTIENGESELLSCHAFT (DE) 1984-12-25 US disclosed