SCHEMBL9436282

SCHEMBL9436282

CC[C@H](C)Cc1cc[c]cc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.35
SIGMAR1 Q99720 3/20 0.32
TAAR1 Q96RJ0 4/20 0.32
SLC6A4 P31645 4/20 0.32
SLC6A2 P23975 2/20 0.32
MAOA P21397 2/20 0.32
SLC6A3 Q01959 1/20 0.32
CYP2A6 P11509 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
ACE P12821 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3080821 1.00 TRPA1 (0.35) TRPA1SIGMAR1TAAR1SLC6A4SLC6A2
SCHEMBL10338368 0.88 BDKRB2 (0.35) TRPA1SIGMAR1SLC6A4ESR1ESR2
SCHEMBL10338370 0.88 BDKRB2 (0.35) TRPA1SIGMAR1SLC6A4ESR1ESR2
SCHEMBL3675392 0.83 ESR1 (0.35) SIGMAR1TAAR1SLC6A4SLC6A2MAOA
SCHEMBL3656635 0.80 SLC6A2 (0.33) SIGMAR1TAAR1SLC6A4SLC6A2MAOA
SCHEMBL1145021 0.80 TRPA1 (0.41) TRPA1SIGMAR1TAAR1SLC6A4SLC6A2
SCHEMBL10497016 0.79 BDKRB2 (0.39) SIGMAR1MAOAESR1ESR2
SCHEMBL3077188 0.79 SLC6A4 (0.34) TRPA1SLC6A4MAOAESR1ESR2
SCHEMBL6887127 0.78 CHRNB2 (0.35)
SCHEMBL28468636 0.78 IDO1 (0.38) TAAR1SLC6A2SLC6A3CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372033-B1 THERMOCHROMIC ESTERS MERCK PATENT GmbH (DE) 1993-08-11 EP claimed
WO-2023137133-A2 PROCESS FOR THE SELECTIVE CATALYTIC HYDROGENATION OF DIENONES BASF SE (DE) 2023-07-20 WO disclosed
EP-0617730-A1 THERMOCHROMIC EFFECT PIGMENT AND PROCESS FOR PRODUCING THE SAME. MERCK PATENT GMBH (DE) 1994-10-05 EP disclosed
WO-1993012195-A1 THERMOCHROMIC EFFECT PIGMENT AND PROCESS FOR PRODUCING THE SAME MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1993-06-24 WO disclosed
WO-1989002093-A1 LIQUID CRYSTAL MICELLES, DISPLAY, HAVING CONCENTRIC SPHERES MOLECULAR CONTROL CORPORATION (US) 1989-03-09 WO disclosed
US-4688901-A Liquid crystal light valve method and apparatus using right and left-handed twist cholesteric liquid crystal JOHNSON LIGHT VALVE INC. (US) 1987-08-25 US disclosed