Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.55 |
| ▸ | MMP3 | P08254 | 5/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | HRH2 | P25021 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6518366 | 0.92 | HDAC1 (0.50) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL9412044 | 0.90 | MMP2 (0.53) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL8939351 | 0.90 | MMP2 (0.67) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL4846755 | 0.86 | MMP3 (0.65) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL3849333 | 0.86 | MMP2 (0.59) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL4408915 | 0.85 | HDAC1 (0.66) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL1274377 | 0.85 | HDAC1 (0.66) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL8939368 | 0.84 | MMP2 (0.73) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL3275879 | 0.83 | MMP2 (0.56) | MMP2MMP3HDAC1HDAC2MMP1 | |
| SCHEMBL13632500 | 0.83 | MMP2 (0.56) | MMP2MMP3HDAC1HDAC2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474713-B1 | (METH)ACRYLATE COPOLYMERIZATES AND THEIR USE IN NON-LINEAR OPTICS AND IN THE PRODUCTION OF LANGMUIR-BLODGETT COATINGS | BASF AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| EP-0290591-B1 | MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS | MERCK PATENT GmbH (DE) | 1991-03-13 | — | — | EP | disclosed |
| EP-0308444-A1 | PYRROL 1.2-b]AZINES | MERCK PATENT GmbH (DE) | 1989-03-29 | — | — | EP | disclosed |
| EP-0290591-A1 | MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS. | MERCK PATENT GMBH (DE) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988007702-A1 | PYRROL [1.2-b]AZINES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |
| WO-1988004305-A1 | MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-06-16 | — | — | WO | disclosed |