Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19602435 | 0.86 | GLA (0.76) | GLAALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL14696849 | 0.85 | GLA (0.74) | GLAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3348685 | 0.84 | GLA (0.73) | GLAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL12793847 | 0.84 | CYP2C9 (0.78) | GLAALDH1A1MAPTKMT2AADRB2 | |
| SCHEMBL14697020 | 0.82 | KMT2A (0.74) | GLAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL26313603 | 0.82 | ALDH1A1 (0.97) | GLAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2981180 | 0.82 | ALDH1A1 (0.97) | GLAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL28352130 | 0.82 | CYP2C9 (0.80) | GLAALDH1A1MAPTKMT2AADRB2 | |
| SCHEMBL12793844 | 0.81 | TDP1 (0.72) | GLAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL14696933 | 0.81 | KMT2A (0.76) | GLAALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110759889-B | 2-aryl amido substituted thiophene imide ester compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2022-05-20 | — | — | CN | disclosed |
| US-20210380546-A1 | VACCINE ADJUVANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-09 | — | — | US | disclosed |
| CN-110759889-A | 2-aryl amido substituted thiophene imide ester compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2020-02-07 | — | — | CN | disclosed |
| US-5292755-A | USPA benzolyguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| US-5091394-A | BENZOYLGUANIDINES, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380546-A1 | VACCINE ADJUVANT | IFNG, TLR9, LY96 | GLA 260/4885ALDH1A1 2763/4885MAPT 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.