Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14697020 | 0.85 | KMT2A (0.74) | GLAALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL9436741 | 0.84 | GLA (1.00) | GLAALDH1A1L3MBTL1KMT2ANPC1 | |
| SCHEMBL14696933 | 0.84 | KMT2A (0.76) | GLAALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL12097479 | 0.83 | CNR1 (0.66) | GLAALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL8246909 | 0.80 | GLA (0.51) | GLAALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL8248648 | 0.79 | FKBP1A (0.59) | GLAALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL16903503 | 0.78 | ALDH1A1 (0.52) | GLAALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL24071356 | 0.77 | GLA (0.49) | GLAALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL16903500 | 0.77 | ALDH1A1 (0.51) | GLAALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL6890933 | 0.77 | GAA (0.69) | GLAALDH1A1GAANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |