Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.45 |
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 6/20 | 0.45 |
| ▸ | CA7 | P43166 | 6/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.45 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115983 | 0.77 | CA1 (0.46) | CA12CA1CA2CA7CA13 | |
| SCHEMBL11855233 | 0.76 | ALDH1A1 (0.55) | CA12CA1CA2CA7CA13 | |
| SCHEMBL8534063 | 0.76 | CA1 (0.42) | CA12CA1CA2CA7CA13 | |
| SCHEMBL20721983 | 0.75 | HPGD (0.55) | LMNAALDH1A1TP53TSHRCASP1 | |
| SCHEMBL7235842 | 0.74 | LMNA (0.47) | LMNA | |
| SCHEMBL670962 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TP53TSHRCASP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9860913 | 0.74 | HPGD (0.53) | LMNAALDH1A1TP53TSHRCASP1 | |
| SCHEMBL4847445 | 0.74 | TSHR (0.52) | LMNAALDH1A1TP53TSHRCASP1 | |
| SCHEMBL20421454 | 0.73 | CA2 (0.46) | CA12CA1CA2CA7CA13 | |
| SCHEMBL2777012 | 0.73 | PTGS1 (0.42) | CA12CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292755-A | USPA benzolyguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |