Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184244 | 0.75 | TSHR (0.54) | MEN1KMT2ANPSR1ALDH1A1KDM4E | |
| SCHEMBL4046417 | 0.72 | MEN1 (0.40) | MEN1KMT2ANPSR1ALDH1A1KDM4E | |
| SCHEMBL2719936 | 0.70 | MAPT (0.46) | MEN1KMT2ANPSR1ALDH1A1KDM4E | |
| SCHEMBL12256781 | 0.67 | SIRT2 (0.38) | GAAMAPK1 | |
| SCHEMBL9876018 | 0.64 | ALPL (0.41) | NPSR1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL3747951 | 0.63 | BACE1 (0.43) | CYP1A2 | |
| SCHEMBL30020352 | 0.62 | HSD17B1 (0.57) | MEN1KMT2ACTDSP1HSD17B1HSD17B2 | |
| SCHEMBL3747955 | 0.62 | SMN1; SMN2 (0.43) | MEN1KMT2ANPSR1ALDH1A1KDM4E | |
| SCHEMBL5697319 | 0.60 | CTDSP1 (0.53) | MEN1KMT2ANPSR1CTDSP1HSD17B1 | |
| SCHEMBL3018108 | 0.60 | ESR1 (0.73) | CTDSP1HSD17B1HSD17B2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359051-A | Compounds useful in the synthesis of nucleic acids capable of cleaning RNA | ISIS PHARMACEUTICALS (US) | 1994-10-25 | — | — | US | disclosed |