Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876158 | 0.73 | LMNA (0.42) | ALPLKDM4ELMNAMCOLN3ALDH1A1 | |
| SCHEMBL9876241 | 0.72 | LMNA (0.41) | ALPLKDM4ELMNAMCOLN3ALDH1A1 | |
| SCHEMBL2184244 | 0.72 | TSHR (0.54) | KDM4ELMNAALDH1A1NPSR1MAPT | |
| SCHEMBL21112178 | 0.71 | GBA1 (0.32) | — | |
| SCHEMBL21112179 | 0.71 | GBA1 (0.32) | — | |
| SCHEMBL9876169 | 0.71 | LMNA (0.43) | ALPLLMNAMCOLN3ALDH1A1HSP90AA1 | |
| SCHEMBL9876901 | 0.70 | LMNA (0.42) | ALPLKDM4ELMNAMCOLN3ALDH1A1 | |
| SCHEMBL9875374 | 0.70 | HTT (0.33) | KDM4ELMNAMCOLN3ALDH1A1NPSR1 | |
| SCHEMBL9876151 | 0.70 | HTT (0.36) | KDM4EMCOLN3ALDH1A1TP53 | |
| SCHEMBL4046417 | 0.70 | MEN1 (0.40) | KDM4ELMNAALDH1A1NPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045557-A | Imidazable fungicides and use thereof | SCHERING AGROCHEMICALS LTD. (GB) | 1991-09-03 | — | — | US | disclosed |
| EP-0284277-A1 | Cyanoimidazole fungicides | AgrEvo UK Limited (GB) | 1988-09-28 | — | — | EP | disclosed |