Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565012 | 0.87 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12330291 | 0.82 | THRB (0.43) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11418593 | 0.80 | THRB (0.41) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11104966 | 0.79 | TSHR (0.46) | TSHRTHRBRELAALDH1A1 | |
| SCHEMBL3256380 | 0.79 | THRB (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4329997 | 0.77 | THRB (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL19514047 | 0.77 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13275508 | 0.77 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3323185 | 0.77 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31303970 | 0.77 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582667-A1 | FLUOROACRYLATE MONOMERS AND POLYMERS, PROCESSES FOR PREPARING THE SAME AND THEIR USE. | MINNESOTA MINING & MFG (US) | 1994-02-16 | — | — | EP | disclosed |