Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437650 | 0.89 | HDAC1 (0.51) | LMNAHDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL9437585 | 0.87 | SOAT2 (0.51) | LMNAHDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL9437480 | 0.77 | MME (0.42) | HDAC1HDAC8HDAC6KMT2AMEN1 | |
| SCHEMBL9026317 | 0.77 | HDAC1 (0.59) | LMNAHDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL28359839 | 0.74 | HDAC1 (0.59) | LMNAHDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL28359843 | 0.74 | HDAC1 (0.59) | LMNAHDAC1HDAC8HDAC6HDAC4 | |
| SCHEMBL4287307 | 0.73 | HDAC1 (0.75) | HDAC1HDAC8HDAC6HDAC4HDAC7 | |
| SCHEMBL7822959 | 0.73 | HDAC1 (0.75) | HDAC1HDAC8HDAC6HDAC4HDAC7 | |
| SCHEMBL17196912 | 0.73 | TP53 (0.90) | TP53MDM2MAPTPKMSTAT3 | |
| SCHEMBL9026182 | 0.71 | KMT2A (0.58) | HDAC1HDAC8HDAC6HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340802-A | Central nervous system disorders | ABBOTT LABORATORIES (US) | 1994-08-23 | — | — | US | disclosed |