Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437630 | 0.84 | F10 (0.41) | F10CTSSF2RENPRSS1 | |
| SCHEMBL9437682 | 0.83 | LMNA (0.43) | LMNACTSSALDH1A1RENPOLB | |
| SCHEMBL9437665 | 0.82 | F2 (0.42) | F10CTSSF2RENPRSS1 | |
| SCHEMBL8909332 | 0.80 | LMNA (0.56) | LMNACTSSALDH1A1POLBMEN1 | |
| SCHEMBL7301756 | 0.80 | LMNA (0.56) | LMNACTSSALDH1A1POLBMEN1 | |
| SCHEMBL7337422 | 0.79 | REN (0.40) | LMNAF10CTSSALDH1A1F2 | |
| SCHEMBL9437608 | 0.77 | LMNA (0.45) | LMNACTSSALDH1A1RENPOLB | |
| SCHEMBL9437606 | 0.77 | LMNA (0.45) | LMNACTSSALDH1A1RENPOLB | |
| SCHEMBL9437644 | 0.75 | LMNA (0.41) | LMNACTSSALDH1A1RENPOLB | |
| SCHEMBL7293036 | 0.75 | MEN1 (0.51) | LMNACTSSALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |