Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | FCER2 | P06734 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 5/20 | 0.38 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.38 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338835 | 0.83 | REN (0.46) | RENMMP1FCER2 | |
| SCHEMBL7338208 | 0.81 | — | — | |
| SCHEMBL7332191 | 0.79 | REN (0.35) | RENHPGDSHSPA1AHSPA5HSPA9 | |
| SCHEMBL7336873 | 0.76 | REN (0.40) | RENMMP1HSPA1AHSPA5HSPA9 | |
| SCHEMBL9437614 | 0.73 | F2 (0.36) | RENALDH1A1TSHR | |
| SCHEMBL9437538 | 0.73 | ALDH1A1 (0.37) | RENALDH1A1TSHRMMP2 | |
| SCHEMBL7330902 | 0.72 | REN (0.36) | RENTSHR | |
| SCHEMBL7330043 | 0.72 | F2 (0.37) | RENTSHR | |
| SCHEMBL9437602 | 0.71 | F2 (0.36) | ALDH1A1TSHRMMP2 | |
| SCHEMBL7331751 | 0.71 | REN (0.54) | RENMMP1FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |