Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437535 | 0.89 | REN (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2REN | |
| SCHEMBL9437573 | 0.84 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2REN | |
| SCHEMBL9437597 | 0.84 | MEN1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2REN | |
| SCHEMBL9437614 | 0.84 | F2 (0.36) | ALDH1A1MEN1KMT2AF2SMN1; SMN2 | |
| SCHEMBL9437653 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2REN | |
| SCHEMBL9437637 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ARENLMNA | |
| SCHEMBL9437602 | 0.80 | F2 (0.36) | ALDH1A1MEN1KMT2AF2SMN1; SMN2 | |
| SCHEMBL9437553 | 0.80 | F2 (0.36) | ALDH1A1MEN1KMT2AF2SMN1; SMN2 | |
| SCHEMBL7338835 | 0.73 | REN (0.46) | REN | |
| SCHEMBL9437652 | 0.73 | REN (0.40) | ALDH1A1RENMMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |