Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437823 | 0.92 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL9437858 | 0.86 | DRD2 (0.37) | SIGMAR1CYP2D6TSHRCYP3A4HRH3 | |
| SCHEMBL8110591 | 0.82 | SIGMAR1 (0.37) | SIGMAR1CYP1A2CYP2D6TP53TSHR | |
| SCHEMBL9437695 | 0.82 | SIGMAR1 (0.37) | SIGMAR1CYP1A2CYP2D6TP53TSHR | |
| SCHEMBL8109727 | 0.82 | SIGMAR1 (0.42) | SIGMAR1CYP1A2CYP2D6TP53TSHR | |
| SCHEMBL8109070 | 0.82 | SIGMAR1 (0.37) | SIGMAR1CYP1A2CYP2D6TP53TSHR | |
| Hydrochloric Acid SCHEMBL8958468 | 0.81 | BLM (0.37) | SIGMAR1CYP1A2CYP2D6TP53TSHR | |
| Hydrochloric Acid SCHEMBL8958474 | 0.81 | SIGMAR1 (0.41) | SIGMAR1CYP1A2CYP2D6TP53TSHR | |
| Hydrochloric Acid SCHEMBL8958874 | 0.81 | BLM (0.37) | SIGMAR1CYP1A2CYP2D6TP53TSHR | |
| SCHEMBL9437753 | 0.81 | SIGMAR1 (0.39) | SIGMAR1CYP1A2CYP2D6TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |