Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437836 | 0.93 | MAPT (0.50) | MAPTSIGMAR1ALDH1A1KDM4ECA12 | |
| SCHEMBL9437772 | 0.83 | HSD17B10 (0.51) | MAPTSIGMAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL9437785 | 0.83 | TSHR (0.49) | MAPTSIGMAR1ALDH1A1KDM4ECA12 | |
| SCHEMBL8870103 | 0.78 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL9437770 | 0.78 | SIGMAR1 (0.54) | SIGMAR1 | |
| SCHEMBL8100626 | 0.78 | SIGMAR1 (0.54) | SIGMAR1 | |
| SCHEMBL8870657 | 0.78 | SIGMAR1 (0.54) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8871595 | 0.77 | SIGMAR1 (0.53) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8871344 | 0.77 | SIGMAR1 (0.54) | SIGMAR1 | |
| SCHEMBL8870642 | 0.76 | SIGMAR1 (0.50) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |