Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437754 | 0.93 | MAPT (0.48) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9437772 | 0.88 | HSD17B10 (0.51) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9437785 | 0.83 | TSHR (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9437692 | 0.76 | SIGMAR1 (0.51) | SIGMAR1 | |
| SCHEMBL8109725 | 0.76 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL8109064 | 0.76 | SIGMAR1 (0.51) | SIGMAR1 | |
| SCHEMBL8110589 | 0.76 | SIGMAR1 (0.51) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8870196 | 0.75 | SIGMAR1 (0.50) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8870179 | 0.75 | SIGMAR1 (0.50) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8870580 | 0.75 | SIGMAR1 (0.52) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |