Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437704 | 0.97 | ACHE (0.46) | ACHE | |
| SCHEMBL9437787 | 0.95 | ACHE (0.44) | ACHE | |
| SCHEMBL9437758 | 0.94 | LMNA (0.40) | ACHEALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9437915 | 0.93 | ACHE (0.46) | ACHE | |
| SCHEMBL9437712 | 0.91 | ACHE (0.41) | ACHE | |
| SCHEMBL8870159 | 0.88 | TDP1 (0.51) | — | |
| SCHEMBL8869440 | 0.87 | CA1 (0.47) | ALDH1A1 | |
| SCHEMBL9556240 | 0.85 | MAOB (0.40) | ACHE | |
| SCHEMBL27311854 | 0.82 | SIGMAR1 (0.50) | — | |
| SCHEMBL9437819 | 0.80 | MAOB (0.45) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |