Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175236 | 0.91 | ALDH1A1 (0.53) | CYP1A2CYP3A4CYP2D6CYP2C9HPGD | |
| SCHEMBL11574369 | 0.83 | CTSL (0.55) | CYP3A4CYP2D6CYP2C9CYP2C19CTSL | |
| SCHEMBL6389667 | 0.82 | CTSL (0.70) | CYP3A4CYP2D6CYP2C9CYP2C19CTSL | |
| SCHEMBL6389671 | 0.82 | CTSL (0.70) | CYP3A4CYP2D6CYP2C9CYP2C19CTSL | |
| SCHEMBL1491409 | 0.82 | CTSL (0.70) | CYP3A4CYP2D6CYP2C9CYP2C19CTSL | |
| SCHEMBL14561285 | 0.82 | CTSL (0.70) | CYP3A4CYP2D6CYP2C9CYP2C19CTSL | |
| SCHEMBL10663359 | 0.82 | CTSL (0.70) | CYP3A4CYP2D6CYP2C9CYP2C19CTSL | |
| SCHEMBL1491407 | 0.82 | CTSL (0.70) | CYP3A4CYP2D6CYP2C9CYP2C19CTSL | |
| SCHEMBL1491412 | 0.82 | CTSL (0.70) | CYP3A4CYP2D6CYP2C9CYP2C19CTSL | |
| SCHEMBL1285941 | 0.82 | CTSL (0.70) | CYP3A4CYP2D6CYP2C9CYP2C19CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302581-A | Administering with lipids for the treatment of respiratory disease | ABBOTT LABORATORIES (US) | 1994-04-12 | — | — | US | disclosed |
| US-5238920-A | Polypeptides mixed with lipids | ABBOTT LABORATORIES (US) | 1993-08-24 | — | — | US | disclosed |