Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27484359 | 0.76 | MEN1 (0.51) | OPRM1OPRL1F2PRSS1F10 | |
| SCHEMBL13201415 | 0.73 | KMT2A (0.55) | OPRM1OPRL1S1PR1ELANE | |
| SCHEMBL17438773 | 0.73 | OPRM1 (1.00) | OPRM1OPRL1OPRD1OPRK1ELANE | |
| SCHEMBL9439215 | 0.73 | OPRM1 (0.47) | OPRM1OPRL1EEF2KF2PRSS1 | |
| SCHEMBL8913362 | 0.69 | F2 (0.47) | OPRM1OPRL1F2PRSS1F10 | |
| SCHEMBL8083108 | 0.69 | F2 (0.57) | F2PRSS1F10MAOAMAOB | |
| SCHEMBL8913564 | 0.68 | F2 (0.44) | OPRM1OPRL1F2PRSS1F10 | |
| SCHEMBL8283693 | 0.68 | DPP4 (0.39) | OPRM1OPRL1F2PRSS1F10 | |
| SCHEMBL13740572 | 0.68 | DPP4 (0.40) | MMP2MMP9F2PRSS1MAOA | |
| SCHEMBL13751285 | 0.68 | DPP4 (0.40) | MMP2MMP9F2PRSS1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346907-A | Cholecystokinin antagonists used in treatment or prevention of disorders of gastrointestinal, central nervous, appetite regulating or pain regulating systems | ABBOTT LABORATORIES (US) | 1994-09-13 | — | — | US | disclosed |