Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 10/20 | 0.45 |
| ▸ | ATIC | P31939 | 5/20 | 0.44 |
| ▸ | TYMS | P04818 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439835 | 0.99 | GART (0.46) | GARTATICTYMS | |
| SCHEMBL9439714 | 0.99 | GART (0.46) | GARTATICTYMS | |
| SCHEMBL9439958 | 0.83 | GART (0.38) | GARTATIC | |
| SCHEMBL8997257 | 0.82 | GART (0.61) | GARTATIC | |
| SCHEMBL9439643 | 0.81 | KMT2A (0.55) | — | |
| SCHEMBL9439648 | 0.81 | KMT2A (0.55) | — | |
| SCHEMBL9439570 | 0.81 | GART (0.58) | GARTATIC | |
| SCHEMBL9220611 | 0.81 | MTHFD1 (0.56) | GARTATIC | |
| SCHEMBL9227822 | 0.80 | DHFR (0.52) | GARTATIC | |
| SCHEMBL9227797 | 0.80 | DHFR (0.57) | GARTATICTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354754-A | Antitumor and -carcinogenic agents; treating human epidermoid carcinoma KB | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |