Mopidamol

Mopidamol

SCHEMBL9440

OCCN(CCO)c1nc(N2CCCCC2)c2nc(N(CCO)CCO)ncc2n1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 19/20 0.72
ADORA3 P0DMS8 2/20 0.72
KDM4E B2RXH2 1/20 0.72
MEN1 O00255 1/20 0.72
PDE2A O00408 1/20 0.72
RGS12 O14924 1/20 0.72
SLC22A2 O15244 1/20 0.72
SLC22A1 O15245 1/20 0.72
ABCC4 O15439 1/20 0.72
ABCC5 O15440 1/20 0.72
PDE6D O43924 1/20 0.72
PDE8A O60658 1/20 0.72
GMNN O75496 1/20 0.72
USP2 O75604 1/20 0.72
PDE5A O76074 1/20 0.72
ABCB11 O95342 1/20 0.72
ALDH1A1 P00352 1/20 0.72
LMNA P02545 1/20 0.72
HSP90AA1 P07900 1/20 0.72
CHRM2 P08172 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mopidamol SCHEMBL30179377 1.00 SLC29A1 (0.72) SLC29A1ADORA3KDM4EMEN1PDE2A
Mopidamol SCHEMBL29352335 1.00 SLC29A1 (0.72) SLC29A1ADORA3KDM4EMEN1PDE2A
Mopidamol SCHEMBL28140838 0.89 SLC29A1 (0.58) SLC29A1ADORA3KDM4EMEN1PDE2A
Mopidamol SCHEMBL28300223 0.85 SLC29A1 (0.53) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL3980595 0.85 SLC29A1 (1.00) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL29381078 0.85 SLC29A1 (1.00) SLC29A1ADORA3KDM4EMEN1PDE2A
SCHEMBL30416820 0.85 SLC29A1 (1.00) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL16119 0.85 SLC29A1 (1.00) SLC29A1ADORA3KDM4EMEN1PDE2A
SCHEMBL2456302 0.84 SLC29A1 (0.49) SLC29A1ADORA3KDM4EMEN1PDE2A
SCHEMBL5055200 0.83 SLC29A1 (0.52) SLC29A1ADORA3KDM4EMEN1PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 19510 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137794-A1 LIGAND-DRUG CONJUGATE AND USE THEREOF SYSTIMMUNE INC (US) 2026-05-21 US claimed
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-20260085100-A1 METHODS OF ANTIGEN PRODUCTION THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) 2026-03-26 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-4694909-A1 METHODS OF MODULATING THE EPITHELIAL-MESENCHYMAL TRANSITION RS Oncology, LLC (US) 2026-02-18 EP claimed
US-12522572-B2 Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-01-13 US claimed
US-20260007763-A1 PEGYLATED ANTIBODY HYDROXYL-BEARING DRUG CONJUGATE SHENZHEN ENDURING BIOTECH, LTD. (CN) 2026-01-08 US claimed
EP-3277381-B1 NITROBENZYL DERIVATIVES OF ANTI-CANCER AGENTS OBI PHARMA INC (TW) 2026-01-07 EP claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 US claimed
EP-0169465-B1 MIXTURE OF PYRIMIDO-PYRIMIDINES AND O-ACETYL-SALICYLIC ACID, OR THEIR PHARMACOLOGICALLY ACCEPTABLE SALTS, AND ITS USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-28 EP claimed
WO-1989011274-A1 CHEMOTHERAPEUTIC COMPOSITION FOR AIDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH (US) 1989-11-30 WO claimed
EP-0306846-A2 Synergistic combination comprising a phosphodiesterase inhibitor and a thromboxane-A2 antagonist, and its use or preparation Dr. Karl Thomae GmbH (DE) 1989-03-15 EP claimed
EP-0257344-A1 Medicaments containing dipyridamol or mopidamol and O-acetylsalicylic acid, or its physiologically compatible salts, process for their manufacture and their use in combating the formation of thrombus Dr. Karl Thomae GmbH (DE) 1988-03-02 EP claimed
US-4694024-A ANTICOAGULANT MIXTURE HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-15 US claimed
US-4650664-A INCREASED BIOAVAILABILITY DR. KARL THOMAE GMBH (DE) 1987-03-17 US claimed
EP-0108898-B1 ORAL GALENICAL FORMS OF MOPIDAMOL Dr. Karl Thomae GmbH (DE) 1986-08-20 EP claimed
US-4596705-A Mopidamol or salt thereof and acid substance in ratio 1:1 DR. KARL THOMAE GMBH (DE) 1986-06-24 US claimed
EP-0169465-A2 Mixture of pyrimido-pyrimidines and O-acetyl-salicylic acid, or their pharmacologically acceptable salts, and its use HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-29 EP claimed
EP-0108898-A1 Oral galenical forms of mopidamol Dr. Karl Thomae GmbH (DE) 1984-05-23 EP claimed