Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CALML3 | P27482 | 1/20 | 0.33 |
| ▸ | ADH5 | P11766 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568448 | 0.90 | PIM1 (0.37) | AKR1C3AKR1C2PRKD3PIM1GSK3A | |
| SCHEMBL9568451 | 0.87 | PIM1 (0.37) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL9568301 | 0.84 | PIM1 (0.35) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL9568435 | 0.84 | PRKAB2 (0.36) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL8323537 | 0.82 | PIM1 (0.41) | TOP2ATOP2BPRKD3PIM1GSK3A | |
| SCHEMBL9522528 | 0.78 | PIM1 (0.39) | PRKD3PIM1GSK3AGSK3BIRAK1 | |
| SCHEMBL9568395 | 0.76 | KDM4E (0.44) | CYP3A4 | |
| SCHEMBL9568459 | 0.73 | PRKCZ (0.44) | — | |
| SCHEMBL9523354 | 0.72 | PRKD3 (0.48) | TOP2ATOP2BPRKD3PIM1GSK3A | |
| SCHEMBL9525097 | 0.72 | PRKD3 (0.47) | TOP2ATOP2BCYP3A4PRKD3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6016678-A | — | — | None | — | — | JP | disclosed |
| JP-H0616678-A | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU CO LTD | 1994-01-25 | — | — | JP | disclosed |
| JP-H00616678-A | — | — | 0001-01-01 | — | — | JP | disclosed |