Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440369 | 0.91 | ALOX5 (0.45) | ALOX5ALDH1A1HPGDMAPT | |
| SCHEMBL9049501 | 0.89 | HPGD (0.47) | ALOX5ALDH1A1HPGDMAPT | |
| SCHEMBL9047280 | 0.86 | ALOX5 (0.46) | ALOX5HPGD | |
| SCHEMBL9440163 | 0.82 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9076633 | 0.82 | ALOX5 (0.40) | ALOX5MAPT | |
| SCHEMBL9076627 | 0.82 | ALOX5 (0.40) | ALOX5MAPT | |
| SCHEMBL9076631 | 0.82 | ALOX5 (0.40) | ALOX5MAPT | |
| SCHEMBL9268618 | 0.81 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9380924 | 0.81 | ALOX5 (0.43) | ALOX5NPSR1MAPT | |
| SCHEMBL9380927 | 0.81 | ALOX5 (0.63) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276037-A | Antiinflammatory agents, antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-04 | — | — | US | disclosed |
| US-5272173-A | 5-lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-21 | — | — | US | disclosed |
| US-5225438-A | Lipoxygenase inhibitors for antiinflammatory agents or antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| EP-0488602-A1 | Aryl derivatives | ZENECA LIMITED (GB) | 1992-06-03 | — | — | EP | disclosed |