Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258471 | 0.85 | MEN1 (0.53) | ALDH1A1MEN1KMT2ASRD5A2HDAC1 | |
| Hydrogen Peroxide SCHEMBL8609891 | 0.84 | PTPN1 (0.52) | ALDH1A1MEN1KMT2AHDAC1SMN1; SMN2 | |
| SCHEMBL1556937 | 0.84 | PTPN1 (0.52) | ALDH1A1MEN1KMT2AHDAC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL258558 | 0.83 | MEN1 (0.51) | ALDH1A1MEN1KMT2ASRD5A2HDAC1 | |
| SCHEMBL7870277 | 0.82 | PGK1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6421413 | 0.81 | MEN1 (0.38) | ALDH1A1MEN1KMT2AHDAC1 | |
| SCHEMBL258557 | 0.80 | MEN1 (0.37) | ALDH1A1MEN1KMT2AHDAC1 | |
| SCHEMBL6421418 | 0.80 | EPHX2 (0.45) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL16239050 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDRAB9ANPC1MEN1 | |
| SCHEMBL272507 | 0.77 | MAPT (0.54) | ALDH1A1HPGDRAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526488-B1 | BENZYLPHOSPHONIC ACID TYROSINE KINASE INHIBITORS | PFIZER (US) | 1994-11-30 | — | — | EP | disclosed |
| US-5326905-A | Benzylphosphonic acid tyrosine kinase inhibitors | PFIZER INC. (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0526488-A1 | BENZYLPHOSPHONIC ACID TYROSINE KINASE INHIBITORS. | PFIZER (US) | 1993-02-10 | — | — | EP | disclosed |
| WO-1991015495-A1 | BENZYLPHOSPHONIC ACID TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1991-10-17 | — | — | WO | disclosed |