Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 3/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474116 | 0.89 | ALOX5 (0.46) | ALOX5MEN1KMT2AALDH1A1HTT | |
| SCHEMBL9440188 | 0.89 | ALOX5 (0.46) | ALOX5MEN1KMT2AALDH1A1HTT | |
| SCHEMBL9394412 | 0.87 | PIK3CD (0.33) | MEN1KMT2AALDH1A1TSHRPIK3CD | |
| SCHEMBL9440178 | 0.84 | MEN1 (0.50) | ALOX5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9694395 | 0.84 | KEAP1 (0.34) | TSHRSMN1; SMN2 | |
| SCHEMBL4143578 | 0.83 | MEN1 (0.42) | ALOX5MEN1KMT2AALDH1A1HTT | |
| SCHEMBL9440202 | 0.82 | MEN1 (0.41) | HRH3ALOX5MEN1KMT2AALDH1A1 | |
| SCHEMBL4141905 | 0.82 | MEN1 (0.41) | HRH3ALOX5MEN1KMT2AALDH1A1 | |
| SCHEMBL9440237 | 0.78 | MEN1 (0.48) | ALOX5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9440179 | 0.76 | MEN1 (0.47) | HRH3ALOX5MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325616-B1 | PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS | WHITBY RESEARCH INC (US) | 1994-07-20 | — | — | EP | disclosed |
| US-5270346-A | Penetration enhancers for transdermal delivery of systemic agents | WHITBY RESEARCH, INC. (US) | 1993-12-14 | — | — | US | disclosed |
| US-5256647-A | Enhanced penetration of skin with antibiotic, bactericides | WHITBY RESEARCH, INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5218113-A | To enhance the penetration of physiologically active agent through the skin or other membrane | WHITBY RESEARCH, INC. (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0257063-B1 | COMPOSITIONS COMPRISING 1-SUBSTITUTED AZACYCLOALKANES AND THEIR USES | WHITBY RESEARCH, Inc. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4992422-A | Enhanced penetration of skin, membranes | WHITBY RESEARCH, INC. (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0325616-A4 | PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS. | NELSON RES & DEV COMPANY (US) | 1989-12-12 | — | — | EP | disclosed |
| EP-0325616-A1 | PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS. | NELSON RES & DEV (US) | 1989-08-02 | — | — | EP | disclosed |
| WO-1988002626-A1 | PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1988-04-21 | — | — | WO | disclosed |