Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL9440430 | 0.94 | PTGER1 (0.49) | PTGER1TSHRLMNAALDH1A1ADRA2A | |
| SCHEMBL9094639 | 0.85 | TSHR (0.49) | TSHRMEN1KMT2ATP53SOAT1 | |
| SCHEMBL2270702 | 0.84 | TSHR (0.48) | TSHRMEN1KMT2ATP53SOAT1 | |
| Potassium Ion SCHEMBL28087603 | 0.80 | MAPK8 (0.53) | PTGER1MAPTCNR2 | |
| SCHEMBL8583652 | 0.79 | SOAT1 (0.51) | TSHRTP53SOAT1PLA2G4B | |
| SCHEMBL2460027 | 0.79 | KDM4E (0.50) | PTGER1TSHRLMNAALDH1A1CYP3A4 | |
| Zinc Ion SCHEMBL9440280 | 0.78 | KCNH2 (0.64) | PTGER1 | |
| SCHEMBL3133224 | 0.78 | OPRM1 (0.43) | TSHRLMNAALDH1A1CYP3A4MEN1 | |
| SCHEMBL2270674 | 0.78 | KDM4E (0.48) | PTGER1TSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL2454872 | 0.77 | MAPT (0.47) | TSHRLMNACYP3A4ADRA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433457-B1 | ANTIPRURITIC COMPOSITION | SHISEIDO CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5219847-A | Antipruritic composition | SHISEIDO COMPANY, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0433457-A1 | ANTIPRURITIC COMPOSITION | SHISEIDO COMPANY LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |