Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL9440334 | 0.94 | PTGER1 (0.45) | PTGER1ADRA2ALMNATP53MAPT | |
| SCHEMBL2460027 | 0.84 | KDM4E (0.50) | PTGER1MAPK8CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL2270674 | 0.83 | KDM4E (0.48) | PTGER1MAPK8CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL3133224 | 0.83 | OPRM1 (0.43) | MAPK8CYP1A2ADRA2AADRA2BADRA2C | |
| Potassium Ion SCHEMBL28087603 | 0.83 | MAPK8 (0.53) | PTGER1MAPK8CYP1A2MAPTCNR2 | |
| SCHEMBL2454872 | 0.82 | MAPT (0.47) | MAPK8CYP1A2ADRA2AADRA2BADRA2C | |
| SCHEMBL9094639 | 0.79 | TSHR (0.49) | TP53TSHRTDP1KDM4EALOX15 | |
| SCHEMBL2520179 | 0.78 | LTA4H (0.50) | CYP1A2LMNAMAPTTSHRL3MBTL1 | |
| SCHEMBL2270702 | 0.78 | TSHR (0.48) | TP53TSHRTDP1KDM4EALOX15 | |
| SCHEMBL25049243 | 0.76 | KDM4E (0.52) | PTGER1MAPK8CYP1A2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433457-B1 | ANTIPRURITIC COMPOSITION | SHISEIDO CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5219847-A | Antipruritic composition | SHISEIDO COMPANY, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0433457-A1 | ANTIPRURITIC COMPOSITION | SHISEIDO COMPANY LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |