Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.67 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.50 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343876 | 1.00 | ITGB3 (0.67) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7356426 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7345863 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7138521 | 0.81 | ALDH1A1 (0.64) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7347492 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL9335890 | 0.81 | ITGB3 (0.71) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL6983843 | 0.80 | ALDH1A1 (0.62) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL7388492 | 0.80 | ITGB3 (0.82) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL8519626 | 0.80 | ITGB3 (0.69) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7390323 | 0.76 | ITGB3 (0.76) | ITGB3ITGA2BF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614360-A1 | SUBSTITUTED -g(b)-AMINO ACID DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS. | SEARLE & CO (US) | 1994-09-14 | — | — | EP | disclosed |