SCHEMBL9440409

SCHEMBL9440409

Ic1ccc(Nc2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.72
HSD17B10 Q99714 5/20 0.72
ALOX12 P18054 4/20 0.72
L3MBTL1 Q9Y468 4/20 0.72
TSHR P16473 4/20 0.72
TDP1 Q9NUW8 4/20 0.72
ALOX15 P16050 2/20 0.72
PTGS1 P23219 1/20 0.72
SLC6A2 P23975 1/20 0.72
MAPK1 P28482 1/20 0.72
PTGS2 P35354 1/20 0.72
HTR2B P41595 1/20 0.72
MAPT P10636 7/20 0.56
CYP3A4 P08684 5/20 0.56
HPGD P15428 3/20 0.56
HTT P42858 2/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
MEN1 O00255 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1306461 0.88 L3MBTL1 (0.50) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL9480038 0.85 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL42930 0.85 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL7896372 0.85 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL13663470 0.85 ALDH1A1 (1.00) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL31212784 0.83 ALDH1A1 (0.67) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL8465009 0.82 ALDH1A1 (0.93) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL26929497 0.82 ALDH1A1 (0.93) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL30067131 0.82 ALDH1A1 (0.93) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL20879853 0.82 LTA4H (0.50) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114890949-B Organic electroluminescent blue light material, preparation method and application thereof, and organic electroluminescent device 山东科技大学 2024-04-09 CN disclosed
CN-114773317-B Acceptor type organic blue light material, preparation method and application thereof, and electroluminescent device 山东科技大学 2024-04-05 CN disclosed
EP-3516019-B1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS CORP (US) 2023-06-14 EP disclosed
CN-114890949-A Organic electroluminescent blue light material, preparation method and application thereof, and organic electroluminescent device 山东科技大学 2022-08-12 CN disclosed
CN-114773317-A Donor-acceptor type organic blue light material, preparation method and application thereof, and electroluminescent device 山东科技大学 2022-07-22 CN disclosed
CN-110305025-B Method for synthesizing benzylamine compound by imine catalytic hydrogenation 衢州学院 2022-05-06 CN disclosed
EP-3309804-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION AND OXIDE SEMICONDUCTOR ELECTRODE Fujifilm Corporation (JP) 2018-04-18 EP disclosed
CN-104394855-A Biomarkers for determining effective response of treatments of hepatocellular carcinoma (HCC) patients Bayer Pharma AG 2015-03-04 CN disclosed
WO-2014077558-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE FOR SAME 덕산하이메탈(주) (KR) 2014-05-22 WO disclosed
CN-103479604-A Derivatives of n-(arylamino) sulfonamides including polymorphs as inhibitors of MEK as well as compositions, methods of use and methods for preparing the same ARDEA BIOSCIENCES INC 2014-01-01 CN disclosed
CN-101808516-B N- (arylamino) sulfonamide derivatives and compositions, including polymorphs, as MEK inhibitors, methods of use, and methods of preparation thereof ARDEA BIOSCIENCES INC 2013-08-28 CN disclosed
CN-101808516-A N- (arylamino) sulfonamide derivatives and compositions, including polymorphs, as MEK inhibitors, methods of use, and methods of preparation thereof ARDEA BIOSCIENCES INC 2010-08-18 CN disclosed
CN-101495118-A N- (arylamino) sulfonamide inhibitors of MEK ARDEA BIOSCIENCES INC (US) 2009-07-29 CN disclosed
US-5276037-A Antiinflammatory agents, antiallergens IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-01-04 US disclosed
US-5272173-A 5-lipoxygenase inhibitors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-21 US disclosed
US-5225438-A Lipoxygenase inhibitors for antiinflammatory agents or antiallergens IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-07-06 US disclosed
EP-0488602-A1 Aryl derivatives ZENECA LIMITED (GB) 1992-06-03 EP disclosed
US-4360511-A Amines useful as brain imaging agents MEDI-PHYSICS, INC. (US) 1982-11-23 US disclosed