SCHEMBL9440567

SCHEMBL9440567

c1cc2c(ccc3scnc32)s1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.36
MAPT P10636 4/20 0.36
ALDH1A1 P00352 3/20 0.36
HTT P42858 2/20 0.36
HPGD P15428 1/20 0.36
PPARG P37231 1/20 0.36
NCOA2 Q15596 1/20 0.36
NCOA1 Q15788 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.35
HTR2C P28335 2/20 0.34
GAA P10253 1/20 0.33
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
HTR2A P28223 3/20 0.32
HTR1A P08908 2/20 0.32
DRD2 P14416 2/20 0.32
CHEK1 O14757 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5160632 0.78 ALDH1A1 (0.46) KDM4EALDH1A1TDP1HSD17B10DYRK1A
SCHEMBL29352476 0.72 KDM4E (0.45) KDM4EMAPTALDH1A1HTTHPGD
SCHEMBL938303 0.71 ALDH1A1 (0.33) ALDH1A1HSD17B10DYRK1ACYP2A6
SCHEMBL9533808 0.71 KDM4E (0.38) KDM4EMAPTALDH1A1HTTHPGD
Bromide SCHEMBL29723865 0.69 ALDH1A1 (0.41) KDM4EMAPTALDH1A1HPGDTDP1
SCHEMBL20186972 0.69 KDM4E (0.39) KDM4EMAPTALDH1A1HTTHPGD
SCHEMBL10054252 0.68 ALDH1A1 (0.38) ALDH1A1HSD17B10DYRK1A
SCHEMBL7072262 0.68 MAPT (0.54) KDM4EMAPTALDH1A1HTTNCOA1
SCHEMBL58137 0.68 LMNA (0.54) KDM4EMAPTALDH1A1HTTTDP1
SCHEMBL29772171 0.68 EGLN1 (0.34) ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2850086-B1 HETEROARYLCYANINE DYES PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2023-07-05 EP disclosed
US-5340710-A Improved sensitivity KONICA CORPORATION (JP) 1994-08-23 US disclosed
US-5166046-A Light sensitive element with sensitizers KONICA CORPORATION (JP) 1992-11-24 US disclosed
EP-0439356-A1 Spectrally sensitized silver halide photographic material KONICA CORPORATION (JP) 1991-07-31 EP disclosed
EP-0323215-A2 Photosensitive silver halide photographic material KONICA CORPORATION (JP) 1989-07-05 EP disclosed