SCHEMBL9440596

SCHEMBL9440596

COc1cccc2cnoc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.47
CHEK1 O14757 1/20 0.43
DAPK3 O43293 1/20 0.43
JAK2 O60674 1/20 0.43
ABL1 P00519 1/20 0.43
NTRK1 P04629 1/20 0.43
RET P07949 1/20 0.43
MET P08581 1/20 0.43
PIM1 P11309 1/20 0.43
MAP2K2 P36507 1/20 0.43
FLT3 P36888 1/20 0.43
MAPK8 P45983 1/20 0.43
GSK3A P49840 1/20 0.43
GSK3B P49841 1/20 0.43
RPS6KA3 P51812 1/20 0.43
LIMK1 P53667 1/20 0.43
TYRO3 Q06418 1/20 0.43
MAP4K2 Q12851 1/20 0.43
PRKAA1 Q13131 1/20 0.43
NTRK2 Q16620 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5573064 0.76 KDM4E (0.61) CHEK1DAPK3JAK2ABL1NTRK1
SCHEMBL10660616 0.74 ALDH1A1 (0.47) CHEK1DAPK3JAK2ABL1NTRK1
SCHEMBL31444190 0.74 ELANE (0.42) CA12CA1CA2CA9
SCHEMBL2056254 0.74 MAOB (0.40) CYP2A6ALDH1A1KDM4ESMN1; SMN2
SCHEMBL4065234 0.72 CHEK1 (0.42) CHEK1DAPK3JAK2ABL1NTRK1
SCHEMBL6968338 0.69 CYP3A4 (0.39) ALDH1A1KDM4ELMNAHPGDKMT2A
SCHEMBL10367732 0.69 KDM4E (0.39) ALDH1A1KDM4ELMNAHPGDRECQL
SCHEMBL5535329 0.69 MAPK14 (0.35)
SCHEMBL30712749 0.69 BRD4 (0.60) CYP2A6CHEK1DAPK3JAK2ABL1
SCHEMBL20778920 0.69 TDO2 (0.37) ALDH1A1KDM4ELMNAHPGDRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5340710-A Improved sensitivity KONICA CORPORATION (JP) 1994-08-23 US disclosed
US-5166046-A Light sensitive element with sensitizers KONICA CORPORATION (JP) 1992-11-24 US disclosed
EP-0439356-A1 Spectrally sensitized silver halide photographic material KONICA CORPORATION (JP) 1991-07-31 EP disclosed
EP-0323215-A2 Photosensitive silver halide photographic material KONICA CORPORATION (JP) 1989-07-05 EP disclosed
US-4053318-A SENSITIZING MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed
US-4047964-A BENZISOXAZOLE FUJI PHOTO FILM CO., LTD. (JA) 1977-09-13 US disclosed
US-4021251-A Silver halide photographic emulsions FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US disclosed