Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660616 | 0.80 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDCHEK1DAPK3 | |
| SCHEMBL9440596 | 0.76 | CYP2A6 (0.47) | KDM4EALDH1A1HPGDCHEK1DAPK3 | |
| SCHEMBL27633733 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDCHEK1DAPK3 | |
| SCHEMBL30879595 | 0.69 | CYP1A2 (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL27499528 | 0.69 | CYP1A2 (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL30701949 | 0.67 | CA9 (0.50) | KDM4EALDH1A1HPGDKMT2ACYP3A4 | |
| SCHEMBL3674074 | 0.67 | CA9 (0.50) | KDM4EALDH1A1HPGDKMT2ACYP3A4 | |
| SCHEMBL4065234 | 0.67 | CHEK1 (0.42) | KDM4EALDH1A1HPGDCHEK1DAPK3 | |
| SCHEMBL3362753 | 0.67 | CA9 (0.70) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL5356684 | 0.65 | TDO2 (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7264951-B1 | Enhanced production of taxol and taxanes by cell cultures of Taxus species | PHYTON, INC. (US) | 2007-09-04 | — | — | US | disclosed |