SCHEMBL9440765

SCHEMBL9440765

CC(Oc1ccccc1CCCCCCCCC(Br)Br)Oc1ccc(Br)c(Br)c1Br

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 5/20 0.35
ADRB1 P08588 5/20 0.35
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9751333 0.88 ADRB2 (0.42) ADRB2ADRB1THRATHRB
SCHEMBL9751186 0.82 ADRB2 (0.36) ADRB2ADRB1
SCHEMBL9751171 0.82 ADRB2 (0.36) ADRB2ADRB1
SCHEMBL9440749 0.82 ADRB2 (0.36) ADRB2ADRB1
SCHEMBL9751205 0.81 ADRB2 (0.34) ADRB2ADRB1
SCHEMBL9440757 0.80
SCHEMBL9440743 0.76 HTR2A (0.36) THRATHRB
SCHEMBL28286670 0.73 HTR1A (0.33)
SCHEMBL332005 0.73 TDP1 (0.34)
SCHEMBL2876410 0.70 LIPG (0.38) ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5346938-A Flame retardant, bicyclic phosphate GREAT LAKES CHEMICAL CORP. (US) 1994-09-13 US disclosed
EP-0500608-A1 SMOKE SUPPRESSED FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITIONS GREAT LAKES CHEMICAL CORPORATION (US) 1992-09-02 EP disclosed
EP-0491870-A1 SMOKE SUPPRESSED FLAME RETARDANT UNSATURATED POLYESTER RESIN COMPOSITIONS GREAT LAKES CHEMICAL CORPORATION (US) 1992-07-01 EP disclosed
EP-0401366-A4 THERMALLY STABLE AND LIGHT STABLE FLAME RETARDANT THERMOPLASTIC POLYOLEFIN AND POLYSTYREN COMPOSITIONS 1991-06-05 EP disclosed
WO-1991004295-A2 SMOKE SUPPRESSED FLAME RETARDANT UNSATURATED POLYESTER RESIN COMPOSITIONS GREAT LAKES CHEMICAL CORPORATION (US) 1991-04-04 WO disclosed
WO-1991004294-A1 SMOKE SUPPRESSED FLAME RETARDANT THERMOPLASTIC RESIN COMPOSITIONS GREAT LAKES CHEMICAL CORPORATION (US) 1991-04-04 WO disclosed
EP-0401366-A1 THERMALLY STABLE AND LIGHT STABLE FLAME RETARDANT THERMOPLASTIC POLYOLEFIN AND POLYSTYREN COMPOSITIONS GREAT LAKES CHEMICAL CORPORATION (US) 1990-12-12 EP disclosed
WO-1990006691-A1 THERMALLY STABLE AND LIGHT STABLE FLAME RETARDANT THERMOPLASTIC POLYOLEFIN AND POLYSTYRENE COMPOSITIONS GREAT LAKES CHEMICAL CORPORATION (US) 1990-06-28 WO disclosed